| Association | : |  Asociación Uruguaya de Fútbol (AUF) |
| Nickname(s) | : | La Celeste (The Sky Blue One), Los Charruas |
| Confederation | : | CONMEBOL |
| FIFA code | : | URU |
| FIFA rank | : | 13 (3 April 2025) |
| Most Caps | : | Diego Godín (161) |
| Top Scorer | : | Luis Suárez (69) |
| Home stadium | : | Estadio Centenario |
| Head coach | : |  Marcelo Bielsa |
Uruguay - FIFA World Cup 26 Qualification
The following 38 players are called up for the 2026 FIFA World Cup qualification matches against Argentina and Bolivia on 21 and 25 March 2025 respectively. Caps and goals correct as of 19 November 2024, after the match against Brazil.
| No | Position | Player | Date of birth (age) | Caps | Goals | Club |
|---|---|---|---|---|---|---|
| GK | Sergio Rochet | 23-03-1993 (31) | 31 | 0 |  Internacional | |
| GK | Santiago Mele | 06-09-1997 (27) | 4 | 0 |  Junior | |
| GK | Franco Israel | 22-04-2000 (24) | 2 | 0 |  Sporting CP | |
| GK | Kevin Martínez | 27-01-2005 (20) | 0 | 0 | Danubio | |
| DF | José María Giménez (captain) | 20-01-1995 (30) | 92 | 8 |  Atlético Madrid | |
| DF | Mathías Olivera | 31-10-1997 (27) | 26 | 2 |  Napoli | |
| DF | Guillermo Varela | 24-03-1993 (31) | 21 | 0 | Flamengo | |
| DF | Ronald Araújo | 07-03-1999 (26) | 20 | 1 | Barcelona | |
| DF | Sebastián Cáceres | 18-08-1999 (25) | 19 | 0 |  América | |
| DF | Joaquín Piquerez | 24-08-1998 (26) | 13 | 0 | Palmeiras | |
| DF | Marcelo Saracchi | 23-04-1998 (26) | 9 | 0 | Boca Juniors | |
| DF | Santiago Bueno | 09-11-1998 (26) | 6 | 0 |  Wolverhampton | |
| DF | José Luis Rodríguez | 14-03-1997 (28) | 3 | 0 | Vasco da Gama | |
| DF | Lucas Agazzi | 02-05-2005 (19) | 0 | 0 | Defensor Sporting | |
| DF | Paolo Calione | 22-05-2006 (18) | 0 | 0 | Nacional | |
| DF | Patricio Pacífico | 08-04-2006 (18) | 0 | 0 | Defensor Sporting | |
| MF | Federico Valverde (vice-captain) | 22-07-1998 (26) | 67 | 8 | Real Madrid | |
| MF | Rodrigo Bentancur | 25-06-1997 (27) | 67 | 3 | Tottenham Hotspur | |
| MF | Nahitan Nández | 28-12-1995 (29) | 65 | 0 |  Al-Qadsiah | |
| MF | Giorgian de Arrascaeta | 01-06-1994 (30) | 53 | 10 | Flamengo | |
| MF | Nicolás de la Cruz | 01-06-1997 (27) | 32 | 5 | Flamengo | |
| MF | Manuel Ugarte | 11-04-2001 (23) | 28 | 1 | Manchester United | |
| MF | Maximiliano Araújo | 15-02-2000 (25) | 20 | 3 | Sporting CP | |
| MF | Nicolás Fonseca | 19-10-1998 (26) | 4 | 0 | León | |
| MF | Emiliano Martínez | 17-08-1999 (25) | 4 | 0 | Palmeiras | |
| MF | Germán Barbas | 17-09-2007 (17) | 0 | 0 | Peñarol | |
| MF | Erico Cuello | 25-05-2005 (19) | 0 | 0 | Defensor Sporting | |
| FW | Darwin Núñez | 24-06-1999 (25) | 33 | 13 | Liverpool | |
| FW | Facundo Pellistri | 20-12-2001 (23) | 32 | 2 |  Panathinaikos | |
| FW | Brian Rodríguez | 20-05-2000 (24) | 26 | 4 | América | |
| FW | Facundo Torres | 13-04-2000 (24) | 19 | 1 | Palmeiras | |
| FW | Cristian Olivera | 17-04-2002 (22) | 11 | 0 | Grêmio | |
| FW | Agustín Álvarez | 19-05-2001 (23) | 4 | 1 | Elche | |
| FW | Luciano Rodríguez | 16-07-2003 (21) | 4 | 0 | Bahia | |
| FW | Rodrigo Aguirre | 01-10-1994 (30) | 2 | 1 | América | |
| FW | Federico Viñas | 30-06-1998 (26) | 2 | 1 | Oviedo | |
| FW | Joaquín Lavega | 03-02-2005 (20) | 0 | 0 | Fluminense | |
| FW | Pablo Suárez | 14-11-2005 (19) | 0 | 0 | Montevideo Wanderers | |
